Peripheral blood Th9 cells and eosinophil apoptosis in allergic asthma patients

نویسندگان

  • Deimante Hoppenot
  • Kestutis Malakauskas
  • Simona Lavinskiene
  • Ieva Bajoriuniene
  • Virginija Kalinauskaite
  • Raimundas Sakalauskas
چکیده

Material and Methods 18 patients with allergic asthma (AA) and 14 patients with allergic rhinitis (AR) were examined. The control group included 16 healthy subjects (HS). All AA and AR patients did not take inhaled corticosteroids at least for one month and/or histamine antagonists at least for one week. Peripheral blood eosinophils and CD4+ cells were isolated by high density gradient centrifugation and magnetic separation. Th9 cells and apoptotic eosinophils were estimated by flow cytometer. Serum interleukin-9 (IL-9) and interleukin-5 (IL-5) level was determined by ELISA.

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عنوان ژورنال:

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2014